AGE1® Designer Cell Lines: Vaccine Platform to Replace Primary Chicken Cells in Vaccine Production

Our designed cell lines, originating from the Muscovy Duck (AGE1.CR®) allow production of a wide spectrum of vaccine strains and viral vectors. An additional modification enhances the susceptibility and yield for some highly attenuated viruses (AGE1.CR.pIX).

Directed immortalization according to the defined risk guidelines of the FDA
Entire development performed in a dedicated GMP suite
Master Cell Bank available
- Extensively characterized according to EU and US guidelines
- Free of adventitious agents and particle associated reverse transcriptase activity
- Full documentation is available for source, cell history and raw materials
High yield, fully scalable and chemically-defined production processes for vaccine viruses established
Successful technology transfers and developments
Permissive for wide spectrum of animal and human viruses, including influenza and pox viruses
Customized packaging cell lines for replication-deficient vectors