Industrial Excellence – Delivering Your Best-Performing Pharmaceutical Production Cell Lines
Whatever the protein you wish to express, you need an optimal cell line, high yielding and stable. You are looking for an experienced specialist with a proven track record in developing cell lines even for challenging proteins – regulatory accepted, fast, reliable. You found it.
In more than 15 years, ProBioGen has developed over 300 stable cell lines for clients in biotech and big pharma, tackling anything from antibodies over bispecific antibodies to some of the most challenging biosimilar recombinant proteins. Thanks to our extensive expertise in upstream and downstream development, we know all the pitfalls and can therefore deliver exceptional and timely results based on a proven and sophisticated process.
Applying our own CHO.RiGHTTM expression vector technology and optimized signal sequences and genes, we select and assess clones under process conditions in our own chemically defined media platform. All final clones are confirmed for optimal cell-metabolic features and product quality, manufacturability, and stability, before Master Cell Bank (MCB) decision. A comprehensive cell line development report for Investigational New Drug (IND) filing is part of every project.
Our process is highly transparent and you will be informed about its progression at every stage.
Advantages of ProBioGen’s CHO.RiGHT® Cell Line Development Platform
- Optimal productivity and product quality
- Demonstrated stability
- Full traceability and regulatory compliance
- Competitive time lines with commitment to milestones
- Fee for service based
- Free of royalty charges
- Unrivalled client satisfaction; ask for customer references